When studying the person-environment relationship between nurses and hospital design, architects and social scientists often maintain a utilitarian view of the nurse as a resource in the hospital system when assessing the degree of efficiency and productivity of nursing care afforded by the design. Instead of this approach I propose a conceptual framework that explores the nurses' perspective of the relationship between their bodies and the design of a hospital unit. Theorizing the body in academia is often limited to the surface of the body and lacks an exploration of the interiority of the corporeal, visceral, and literal body (Birke, 1999). The act of nursing places a stressful burden on hospital nurses' bodies by impacting their interior body. The nature of the physicality of hospital nurses' work is marginalized in nursing professionalism literature. An analysis of the time-body-space relationship of the nurse and the hospital unit calls for an in-depth qualitative investigation that illuminates the complexity of this interdependent relationship.