In an outline of the state of the art the author attempts to highlight mutual interrelations between medicine and architecture. The paper starts with a short historic overview on health and hygiene relevance of patterns of urbanisation and residential architecture. then covers psychological issues in the criticism of post war mass housing. discusses health relevance of comfort and physiological problems and leads to new concerns about.toxic and allergenic materials in the physical environment. Radiation and geobiology are covered as well. Finally the lack of transdisciplinary research is complained about and the need for residential medicine as a subject of architectural teaching is emphasized. Examples from author's own enquiries and from recent german literature are quoted.