The sense of spatial identity is a concept introduced to provide a spatial context for many human experiences and behaviors (Fried, 1963). The subsequent conceptualization of place identity (Proshansky and Kaminoff, 1982) further delineated numerous functions subserved by this form of self-identity. Much evidence, widely dispersed, confirms the critical significance of place orientations for human development and functioning and as a dominant factor in adaptation to environmental stress. This paper examines the socio-cultural and psychobiological core of place identity and of manifest variations within and across societies. It presents a fundernantal theoretical formulation of the sense of place and its psychological intergrative fontioris.