The housing niche model describes: 1) forces that lead people to locate into the residential environment; 2) the bundle of assets, threats, hazards, and opportunities associated with living in a particular location; 3) implications for health, asset accumulation and future mobility and health (Saegert & Evans, 2003). As a result of U.S. housing markets and policies, low income people often inhabit housing that is of poor quality, in hazardous neighborhoods, and too costly for their resources. Poverty contributes to poor housing, and to poor health directly. The housing niche affects physical and mental health indirectly as a result of environmental hazards, the psychological stress associated with hazards and poverty, and the burden stress places on family relationships. Housing niche dynamics are illustrated by two studies of exposure to stressors and their relationship to psychological and physiological stress, and family dynamics among poor residents of urban public and rural rental housing.