"The research aims at exploring the transition of human-place relationship. A case study of relocation helps to examine how place identity and place attachment are formed in the process of interaction among individuals, community, and their environment, and how they rebuild the identity and attachment after the physical environment changed. "Fish-house" was a cozy, independent one-story house a free space for students of Zoology Department in National Taiwan University. The students used to spend their leisure time there. However, all students had to leave their familiar place and move to a new building of twelve stories, namely "Life Science Hall". Although there is a room preserved for students, existence of disparate spatial qualities between both, such as inner space, outdoor space, and location, induced negative and resisting reactions of interviewees. Thereafter, the alienated room was transformed into a meaningful "fish-house" through continuing process of shaping the sense of spatial continuity, coordination among groups, and creating new experience. Data collection included in-depth interviews pre- and post-relocation as well as archival studies in order to realize the meaning-building ways and process of "fish-house", and the impact of the moves. The process of the relocation was related to the disruption and regeneration of place attachment. New place identity is due to the accumulation of new interaction and the interactional potential provided by new space. "Fish-house" is regarded as a behavior setting, and the life cycle of the setting is described in the research. The transition of the human-place relationship has much to do with the life cycle of the behavior setting. Generally speaking, if a setting is in its growing phase, the members can create new experiences and generate new meanings more easily, therefore they can rebuild place attachment and place identity more readily in a new place."