The Architecture of Higher Education Buildings in Turkey: A well- formulated and designed high education sites and buildings define the place of university in the community and in the history, because the importance of visual and cultural effects can not be denied. All humans are part of a certain cultural structure. In this structure, there is law, education, religions. All these systems are effective as superstructure of culture. The science and the arts affect the human’s cultural life too. Besides of these effects, architectural designs achieve aesthetic satisfaction, by arrangement of campus plan, by responding to variations in topography and tree cover, by organizing some approaches, enters, passes, vistas. The purpose of the study is to indicate and examine the most important aesthetical and cultural aspects of the architecture for higher education buildings in Turkey, in the case of _zmir Institute of Technology buildings. Effects of Culture in The Essence and Form of Higher Education Buildings The essence of architecture is the function. Function comes from human’s behaviours and from his cultural activities in life. Function sometimes differs from culture to culture. The production forces, the production relations, then the production system of any country, all these things are infrastructure of a culture as economical system. For the creation of cultural structure of human beings, the science and the arts are effective factors. Besides, sociological and ideological structures form community life as organisms and the family system also forms community life as cell in a culture. Human as an information source makes cultural effects to the community and as well as community make humans to be cultured. And human is effected from cultural structure as an information. Function occurs in a culture. Function effects the architectural designs of Higher Education Buildings. Then the essence and the form of Higher Education Buildings are related to culture. Case Studies from Turkey: This study is a part of a widespread study about aesthetical concepts in the architecture of higher education buildings. The subject is evaluated starting from the general topic ‘Effects of Culture in the Architecture of Higher Education Buildings in Turkey’. Case studies are from Turkey, especially _zmir Institute of Technology Buildings. While researching about University buildings some field studies are done in some University buildings in and outside Turkey. This study argues that in each culture and in each time period, architecture is changing as cultural and aesthetical changes occurred. Local and Global Effects of Cultures for Higher Education Buildings in Turkey : The architecture of Higher Education buildings must be local and global. While university effects from local culture, this is a universal environment for every country in the world. Nowadays, to understand the essence, form and culture for university buildings environment, the cultural system in that country must be well understood. It is necessary to investigate whether to preserve this existing environment which has a conformist aesthetic agenda or to change it in a revolutionary manner creating a new culture which will open up new horizons- to virtual reality which are not existing. This is where the basis of the problem exists. The architecture of higher education buildings must be local and global. It should be created by being rooted in one’s own history and culture and at the same time making positive efforts to incorporate elements from heterogeneous cultures.