"Making the guideline for planning and designing the playroom: This research aims to study the relationship between the physical environment and the activities of profoundly multiple handicapped children. We wanted to make the guideline for planning and designing the no.2 playroom at the facility for therapy and education of the children in Chiba Higashi Hospital through this research. Create more healing and playful environment: We renovated another playroom at no.3 ward for pediatrics in Chiba Higashi Hospital in 2004. The previous playroom used to be unattractive, so staff which was mainly child- care workers and child guidance workers, wished to design more healing and playful environment. We conducted post-occupancy evaluation on the new playroom and we found its new environment created more children's imaginative activities and also offered more comfortable space for parents. Because of the great success of the renovation, we were asked to renovate another playroom at facility for therapy and education of children.Three therapeutic activities: In this research we used the observational survey for understanding the activities of the children._We spent 4 days for doing this observational survey._The activities we observed were follows: 1) Therapeutic activities on multi sensory stimulation called "snoezelen":_Staff makes the settings with multi sensory stimulated equipments for these activities. 2) Therapeutic activities on multi sensory stimulation with music: Staff sings and show musical instruments to the children. They also let them to touch the musical instruments for their sensory stimulation. 3) Therapeutic activities on motor stimulation called "movement": This isn't training but pleasure activity with movement to develop mind and body. This activity only works on specific person for a half year to one year. Besides the observational survey, we did interviews to staff about these activities, the life and physical condition of the children. Relationship between activities and settings: We found the relationship between theses activities and settings. The children especially showed very strong emotion against sound, light, smell and tremble. The setting was always changed according to the type of therapeutic activity. In "snoezelen" and music therapy, the children used no.1 playroom. However, in "movement," they also used no.2 playroom as well. Because "movement" gave much mental stress on the children, so they should be calmed down for a while in no.2 playroom before going back to their bedrooms. They used two different rooms, one was for the therapy and another was for the relaxation."