Adapted treatment environments to specific mental handicapping diseases have been shown to have beneficial effects on a certain number of symptoms. Treatment environments have been particularly studied on elderly pathological and non-pathological populations as well as youngsters. Autistic individuals are also known to have a peculiar relation with their environment but little has been done so far in this perspective. First described by Kanner in 1943, autism is a neurodevelopmental disorder associating three major areas of impairments and dysfunctioning: social; interaction and communication; excessive focused interests. Autistic individuals were primarily considered as unable to differentiate themselves from their environment, using social or physical environmental items as extensions of their own body. However, research on heredity of autistic symptoms report an important contribution of environmental factors. In addition, several researchers have recently underlined a significant effect of social and physical environmental settings on their studied autistic behaviors and cognitive processes. As a matter of fact, clinicians and caregivers also report that environmental settings seem to be related to disruptive behaviors such as agitation, ideational or behavioral stereotypy, self-injurious behaviors or aggressive behaviors, as well as social withdrawal and other non-adapted behaviors. In order to examine the possible relationships between autistics individuals and their environment through a transactional approach, we propose to enlighten this topic through the existent theoretical and empirical corpus in terms of practices, autobiographical manuscripts, and related research. We will then deepen this corpus with collected data concerning observed environmental variables influencing autistic behaviors through interviews of caregivers, parents of autistic children and experts in autism on the studied topic. Finally, the previously collected data is tested by observation of autistic individuals’ behaviors in specific nursing homes.In this poster we will present our data through the observed behavioral effects of environmental design characteristics on autistic spectrum disorders, based on the information we gathered through our research and inspired of previous Environment-Behavior models related to other psychopathologies. We also discuss environmental changes related to our observations in the perspective of elaborating autism friendly environments.