Purpose: Current research on restorative environments often includes healthy individuals and frequently utilizes laboratory settings to create intended antecedent conditions. Outside of the horticultural therapy literature and retrospective examination of hospital records, unhealthy populations generally are not included as participants. While this trend is reversing, these endeavors have not yet included individuals with head and neck cancer (HNCa). The purpose of this study was to determine if individuals receiving chemotherapy for the treatment of HNCa experience changes in directed attention, mood, and symptom distress following “green experiences”. Research Questions: This study explored two research questions: 1) can slideshows of restorative environments effectively be shown in the home setting to produce green experiences, and 2) do individuals receiving chemotherapy experience changes in directed attention, mood, and symptom distress as a result of such simulated green experiences (i.e., via slideshows of restorative environments). Method: Using a multiple baseline across subjects design, 6 participants who received chemotherapy as treatment for HNCa were included. Participants completed a 13-day home-based protocol that included viewing slideshows of restorative environments and completing the Necker Cube Pattern Control test, the Zuckerman Inventory of Personal Reactions, and the Edmonton Symptom Assessment Scale. Results & Conclusions: While individual variability is characteristic of the study population, the viability of utilizing green experiences may result in significant respite from the effects of treatment in some individuals. Implications of these data to active treatment rehabilitation efforts will be discussed. Significance of Project: This work is important in that it seeks to maintain and foster human-nature relationships for those who are ill and experience reduced quality of life. Given the toxic effects of chemotherapy, individuals may not be in a position to directly seek out green experiences. Therefore, introduction of green experiences via home-based slideshows may reveal benefits to one’s perceived health, well-being, and quality of life during cancer treatment. These data may support further integration of nature-based activities in treatment and rehabilitative protocols.