When new ideas and technologies are being disseminated to new beneficiaries, the most important success factor of sustainable uptake of the innovation is – generally spoken – a high degree of presence and acceptance of the innovation in the target community or society. To establish this well-embeddedness, interpersonal communication plays a very important role. Communication about the innovation not only facilitates constant exchange and presence of the topic, but also allows for self-diffusion beyond the initial key target subjects. Additionally, knowledge is passed on, convictions and attitudes are discussed and refined and implicit norms are built. Therefore, it appears to be extremely valuable to investigate the antecedents influencing if and how frequently people communicate about the promoted innovation. The present study investigates factors influencing communication behavior about a health innovation at different time points of the innovation promotion process. Results show that the main factors influencing communication intensity are problem awareness and involvement, intention to use the innovation, normative influence, and affective attitude towards talking about the innovation. Further influence when the innovation is already in use was found in frequency of forgetting and perceiving forgetting as highly dissonant. Influence factors were fairly stable over time. Other factors such as depth of knowledge, attitude and attitude components towards the innovation itself did not show influence in the regression models. Discussion includes possible explanations, including theoretical and practical aspects, and considerations which other factors could help to understand why people talk about a certain topic or innovation and why not. An outlook will be given on ways how to facilitate interpersonal communication about an innovation in an applied context.